Research
What the science says.
Every active ingredient in the Mindly range, cross-referenced with independent research: the NIH Office of Dietary Supplements, Oregon State’s Linus Pauling Institute, Examine, and the NCCIH.
Joints
Glucosamine
An amino sugar the body uses to build cartilage. Most clinical trials look at glucosamine sulfate at around 1,500mg/day for knee osteoarthritis. Evidence is mixed but lean: many people report reduced stiffness and pain over weeks, with the strongest signal in moderate joint discomfort rather than severe disease.
Chondroitin
A long-chain molecule that's a major component of cartilage. Often paired with glucosamine. Clinical trials show small-to-moderate improvements in joint comfort and function in osteoarthritis, with effects building over months rather than days.
MSM (Methylsulfonylmethane)
A bioavailable form of sulfur — a building block for collagen, keratin and connective tissue. Trials at doses around 1.5–6g/day suggest reduced joint pain and stiffness in osteoarthritis. Generally well-tolerated.
Beauty
Hydrolyzed Collagen
The most abundant structural protein in the body — declines steadily after age 25. Hydrolyzed collagen peptides are absorbable amino-acid fragments shown in trials to support skin elasticity, hydration, and nail strength after 8–12 weeks. Early evidence suggests joint comfort benefits at 5–10g/day.
Energy
L-Carnitine
An amino acid derivative that shuttles long-chain fatty acids into mitochondria, where they are oxidised for energy. The L-tartrate form is favoured for absorption in physically active populations. Evidence is strongest for reduced muscle damage and faster recovery after intense training.
Taurine
A sulfur-containing amino acid the body produces in modest amounts. Plays a role in bile-salt formation, cardiovascular function, and protecting tissues from oxidative stress. Supplementation at 1–3g/day is well-studied for blood-pressure support and athletic recovery.
Antioxidant
Curcumin (with piperine)
The active polyphenol in turmeric. On its own curcumin has poor oral bioavailability — but paired with piperine from black pepper, absorption increases roughly twentyfold. Evidence is strongest for reducing markers of inflammation, supporting joint comfort in osteoarthritis, and modest improvements in cardiometabolic markers.
Ginger
A traditional herb with a strong evidence base for nausea (motion sickness, pregnancy, post-surgery) and a moderate one for menstrual pain and exercise-induced muscle soreness. Acts as a mild anti-inflammatory.
Vitamin C (with bioflavonoids and rose hips)
An essential water-soluble antioxidant the body cannot synthesise. Required for collagen synthesis, iron absorption, and immune-cell function. Bioflavonoids and rose-hip extract — both naturally co-occurring with vitamin C in fruit — improve absorption and extend antioxidant activity in some studies.
Foundations
Calcium
The most abundant mineral in the body, primarily stored in bone. Adequate intake supports bone-mineral density across the lifespan and is especially important during adolescent growth and post-menopause. Best absorbed with vitamin D3 and in doses ≤500mg at a time.
Magnesium
A cofactor in over 300 enzymatic reactions including muscle and nerve function, blood-pressure regulation, and bone formation. Modern diets often fall short of the RDA. Supplementation at 200–400mg/day is associated with improved sleep quality, reduced muscle cramps, and better stress resilience.
Zinc
Essential for over 100 enzymes, immune cell function, wound healing, and protein synthesis. Short-term supplementation can shorten the duration of common-cold symptoms. Long-term intake should stay within recommended limits to avoid interfering with copper absorption.
Vitamin D3 (Cholecalciferol)
A fat-soluble vitamin synthesised in skin from sunlight and obtained from a small number of foods. Required for calcium absorption, bone health, and immune regulation. Insufficiency is widespread at northern latitudes and during winter months. D3 (cholecalciferol) is the form humans produce naturally.
Cognitive
Active B vitamins (B6 P5P, B9 Methylfolate, B12 Methylcobalamin)
B6, B9 and B12 work together in homocysteine metabolism, red-blood-cell production, and nervous-system function. The 'active' forms — pyridoxal-5-phosphate (P5P), methylfolate (5-MTHF), and methylcobalamin — bypass the conversion steps inactive forms require. This matters especially for the meaningful percentage of people with reduced MTHFR enzyme activity.